Polio vaccine trials begin
On April 26, 1954, the Salk polio vaccine field trials, involving 1.8 million children, begin at the Franklin Sherman Elementary School in McLean, Virginia. Children in the United States, Canada and Finland participated in the trials, which used for the first time the now-standard double-blind method, whereby neither the patient nor attending doctor knew if the inoculation was the vaccine or a placebo.
On year later, on April 12, 1955, researchers announced the vaccine was safe and effective and it quickly became a standard part of childhood immunizations in America. In the ensuing decades, polio vaccines would all but wipe out the highly contagious disease in the Western Hemisphere.
Polio, known officially as poliomyelitis, is an infectious disease that has existed since ancient times and is caused by a virus. It occurs most commonly in children and can result in paralysis. The disease reached epidemic proportions throughout the first half of the 20th century. During the 1940s and 1950s, polio was associated with the iron lung, a large metal tank designed to help polio victims suffering from respiratory paralysis breathe.
President Franklin Roosevelt was diagnosed with polio in 1921 at the age of 39 and was left paralyzed from the waist down and forced to use leg braces and a wheelchair for the rest of his life. In 1938, Roosevelt helped found the National Foundation for Infantile Paralysis, later renamed the March of Dimes. The organization was responsible for funding much of the research concerning the disease, including the Salk vaccine trials.
The man behind the original vaccine was New York-born physician and epidemiologist Jonas Salk (1914-95). Salk’s work on an anti-influenza vaccine in the 1940s, while at the University of Michigan School of Public Health, led him, in 1952 at the University of Pittsburgh, to develop the inactivated polio vaccine (IPV), based on a killed-virus strain of the disease. The 1954 field trials that followed, the largest in U.S. history at the time, were led by Salk’s former University of Michigan colleague, Dr. Thomas Francis, Jr.
In the late 1950s, Polish-born physician and virologist Albert Sabin (1906-1993) tested an oral polio vaccine (OPV) he had created from a weakened live virus. The vaccine, easier to administer and cheaper to produce than Salk’s, became available for use in America in the early 1960s and eventually replaced Salk’s as the vaccine of choice in most countries.
Today, polio has been eliminated throughout much of the world due to the vaccine; however, there is still no cure for the disease and it persists in a small number of countries in Africa and Asia.
CRIME
2012
Former Liberian president Charles Taylor found guilty of war crimes
On April 26, 2012, former Liberian president Charles Taylor is found guilty of abetting horrific war crimes, including rape and mutilation in Sierra Leone. His conviction was the first for war crimes by a former head of state in an international court since the Nuremberg trials.
NATURAL DISASTERS & ENVIRONMENT
1986
Test triggers nuclear disaster at Chernobyl
On April 26, 1986, the world’s worst nuclear power plant accident occurs at the Chernobyl nuclear power station in the Soviet Union. Thirty-two people died and dozens more suffered radiation burns in the opening days of the crisis
WORLD WAR II
1937
Nazis test new air force, Luftwaffe, on Basque town of Guernica
During the Spanish Civil War, the German military tests its powerful new air force—the Luftwaffe—on the Basque town of Guernica in northern Spain. Although the independence-minded Basque region opposed General Francisco Franco’s Nationalist forces in the Spanish Civil War.
U.S. PRESIDENTS
1984
President Reagan visits China
On April 26, 1984, President Ronald Reagan arrives in China for a diplomatic meeting with Chinese President Li Xiannian. The trip marked the third time a U.S. president had traveled to China since President Richard Nixon’s historic trip in 1972 (Gerald Ford visited in 1975).
WESTWARD EXPANSION
1798
Mountain man James Beckwourth is born
James Beckwourth, one of only a handful of early mountain men to emerge from the system of slavery, is born in Fredericksburg, Virginia. The exact year of Beckwourth’s birth is in dispute. Some historians suggest it may have been 1800 rather than 1798.
ART, LITERATURE, AND FILM HISTORY
1977
Studio 54 opens in New York City
The crowd outside 254 West 54th Street in New York City on this day in 1927 would have been waiting for the curtain of a Puccini opera. On this day in 1957 or ’67, they would have been waiting for a filming of an episode of Password or maybe Captain Kangaroo.
ART, LITERATURE, AND FILM HISTORY
1986
Maria Shriver marries Arnold Schwarzenegger
Almost a decade after they met at a celebrity tennis tournament, the television news reporter Maria Shriver marries the movie actor and former bodybuilder Arnold Schwarzenegger on April 26, 1986.
CRIME
1913
Thirteen-year-old girl murdered in Atlanta pencil factory
Thirteen-year-old Mary Phagan is found sexually molested and murdered in the basement of the Atlanta, Georgia, pencil factory where she worked. Her murder later led to one of the most disgraceful episodes of bigotry, injustice and mob violence in American history.
1950S
1954
Geneva Conference to resolve problems in Asia begins
In an effort to resolve several problems in Asia, including the war between the French and Vietnamese nationalists in Indochina, representatives from the world’s powers meet in Geneva. The conference marked a turning point in the United States’ involvement in Vietnam.
CIVIL WAR
1865
Lincoln assassin John Wilkes Booth dies
John Wilkes Booth is killed when Union soldiers track him down to a Virginia farm 12 days after he assassinated President Abraham Lincoln. Twenty-six-year-old Booth was one of the most famous actors in the country when he shot Lincoln during a performance at Ford’s Theater.
WORLD WAR I
1915
Allies sign Treaty of London
On April 26, 1915, after receiving the promise of significant territorial gains, Italy signs the Treaty of London, committing itself to enter World War I on the side of the Allies. With the threat of imminent war looming in July 1914, the Italian army under Chief of Staff Luigi.
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